Title : Lentivirus-shRNA mediated prolyl hydroxylase 2 knockdown increases HIF-1α and inhibits nucleus pulposus cells degeneration.

Pub. Date : 2021 Nov 15

PMID : 34781297






1 Functional Relationships(s)
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1 In addition, the oxygen-dependent conversion of HIF-1alpha in nucleus pulposus cells is controlled by the protein Proline 4-hydroxylase domain (PHD) family. Proline hypoxia inducible factor 1 subunit alpha Homo sapiens