Title : Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells.

Pub. Date : 2021 Nov 12

PMID : 34773067






1 Functional Relationships(s)
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1 As hypothesized, we also found that ouabain, digitoxin and digoxin blocked penetration by SARS-CoV-2 Spike-pseudotyped virus into human lung cells, and infectivity by native SARS-CoV-2. Digoxin surface glycoprotein Severe acute respiratory syndrome coronavirus 2