Title : Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages.

Pub. Date : 2021 Oct 27

PMID : 34770896






1 Functional Relationships(s)
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1 The western blots analysis of COX-2 and iNOS showed that the PGE2 and NO inhibitory effect of compound 1m are attributed to inhibition of COX-2 and iNOS protein expression through inactivation of p38. Dinoprostone mitogen-activated protein kinase 14 Mus musculus