Title : Tenofovir Modulates Semaphorin 4D Signaling and Regulates Bone Homeostasis, Which Can Be Counteracted by Dipyridamole and Adenosine A2A Receptor.

Pub. Date : 2021 Oct 25

PMID : 34768920






1 Functional Relationships(s)
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1 pRhoA and ROCK1 activation were increased and IRS1/IGF1R expression was diminished by tenofovir in the Vav3/ARHGAP18 mechanism in osteoblast precursors and reverted by dipyridamole in an A2A-dependent manner. Tenofovir insulin-like growth factor I receptor Mus musculus