Title : Targeting Epigenetic Modifiers Can Reduce the Clonogenic Capacities of Sézary Cells.

Pub. Date : 2021

PMID : 34765562






1 Functional Relationships(s)
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1 We previously reported that Histone deacetylase inhibitors (HDACi, romidespin and vorinostat) and a DNA methyltransferase inhibitor (DNMTi, 5-azacytidine) can reduce hTERT expression without altering the methylation level of hTERT promoter. Azacitidine telomerase reverse transcriptase Homo sapiens