Pub. Date : 2022 Jan
PMID : 34763314
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway. | Reactive Oxygen Species | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Moreover, these elevated levels of the proteins were inhibited by the antioxidant N-acetylcysteine and the JNK inhibitor SP600125, suggesting the involvement of ROS/JNK-dependent mechanisms in AGS-30-induced apoptosis. | Reactive Oxygen Species | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Moreover, these elevated levels of the proteins were inhibited by the antioxidant N-acetylcysteine and the JNK inhibitor SP600125, suggesting the involvement of ROS/JNK-dependent mechanisms in AGS-30-induced apoptosis. | Reactive Oxygen Species | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | AGS-30 induces apoptosis of colon cancer cells through ROS/JNK-dependent pathway. | Reactive Oxygen Species | mitogen-activated protein kinase 8 | Homo sapiens |