Pub. Date : 2021 Nov 10
PMID : 34758839
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lactate induces aberration in the miR-30a-DBF4 axis to promote the development of gastric cancer and weakens the sensitivity to 5-Fu. | Lactic Acid | microRNA 30a | Homo sapiens |
| 2 | The important composition in tumor microenvironment, lactate, may be the primary factor that suppressed miR-30a to strengthen the expression of DBF4. | Lactic Acid | microRNA 30a | Homo sapiens |
| 3 | Furthermore, our study identified the lactate-miR-30a-DBF4 axis as a crucial regulator of tumor progression and the tumor sensitivity to 5-Fu, which maybe serve useful for the development of novel therapeutic targets. | Lactic Acid | microRNA 30a | Homo sapiens |