Pub. Date : 2022 Feb
PMID : 34748921
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dietary supplementation of TB significantly increased skin temperature of the inguinal region in mice and induced the expression of UCP1 protein. | Theobromine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |
| 2 | Furthermore, in mouse-derived primary adipocytes, TB upregulated the expression of the UCP1 protein and mitochondrial mass in a PPARgamma ligand-dependent manner. | Theobromine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |
| 3 | These results indicate that dietary supplementation of TB induces browning in subcutaneous WAT and enhances PPARgamma-induced UCP1 expression in vitro, suggesting its potential to treat obesity. | Theobromine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |