Title : The modulation of SIRT1 and SIRT3 by natural compounds as a therapeutic target in doxorubicin-induced cardiotoxicity: A review.

Pub. Date : 2022 Jan

PMID : 34747550






1 Functional Relationships(s)
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1 Numerous NCs exerted their therapeutic effects on DOX-mediated cardiac damage via targeting different signaling pathways, including SIRT1/LKB1/AMPK, SIRT1/PGC-1alpha, SIRT1/NLRP3, and SIRT3/FoxO. Doxorubicin NLR family pyrin domain containing 3 Homo sapiens