Pub. Date : 2021
PMID : 34719651
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exposure to Stearate Activates the IRE1alpha/XBP-1 Pathway in 3T3-L1 Adipocytes. | Stearates | X-box binding protein 1 | Homo sapiens |
| 2 | Exposure to stearate for several hours elevated the ratio of spliced XBP-1 mRNA, and this effect was stronger than that of palmitate. | Stearates | X-box binding protein 1 | Homo sapiens |
| 3 | Thus, in adipocytes, exposure to stearate activates the UPR via the IRE1alpha/XBP-1 pathway, but not the PERK/CHOP and ATF6alpha pathway. | Stearates | X-box binding protein 1 | Homo sapiens |