Title : Bacterial Subversion of Autophagy in Cystic Fibrosis.

Pub. Date : 2021

PMID : 34692569






1 Functional Relationships(s)
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1 The loss of CFTR function alters chloride, bicarbonate, and water transport through the plasma membrane, promoting the production of a thick and sticky mucus in which bacteria including Pseudomonas aeruginosa and Burkholderia cenocepacia can produce chronic infections that eventually decrease the lung function and increase the risk of mortality. Bicarbonates CF transmembrane conductance regulator Homo sapiens