Title : 7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway.

Pub. Date : 2021 Oct 2

PMID : 34685613






3 Functional Relationships(s)
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1 Furthermore, the MAPK inhibitors indicated that 7-Epitaxol induces apoptosis and autophagy marker proteins (cleaved-PARP and LC3-I/II) by reducing the phosphorylation of ERK1/2. Paclitaxel mitogen-activated protein kinase 3 Homo sapiens
2 In conclusion, these findings indicate the involvement of 7-Epitaxol in inducing apoptosis and autophagy through ERK1/2 signaling pathway, which identify 7-Epitaxol as a potent cytotoxic agent in HNSCC. Paclitaxel mitogen-activated protein kinase 3 Homo sapiens
3 In conclusion, these findings indicate the involvement of 7-Epitaxol in inducing apoptosis and autophagy through ERK1/2 signaling pathway, which identify 7-Epitaxol as a potent cytotoxic agent in HNSCC. Paclitaxel mitogen-activated protein kinase 3 Homo sapiens