Title : Troglitazone-Induced PRODH/POX-Dependent Apoptosis Occurs in the Absence of Estradiol or ERĪ² in ER-Negative Breast Cancer Cells.

Pub. Date : 2021 Oct 10

PMID : 34682765






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 PRODH/POX degrades proline yielding reactive oxygen species (ROS). Proline proline dehydrogenase 1 Homo sapiens
2 PRODH/POX degrades proline yielding reactive oxygen species (ROS). Proline proline dehydrogenase 1 Homo sapiens
3 The data suggest that TGZ-induced apoptosis in MDA-MB-231 cells cultured in medium without estradiol or deprived of ERbeta is mediated by PRODH/POX and the process is facilitated by proline availability for PRODH/POX by TGZ-dependent inhibition of collagen biosynthesis. Proline proline dehydrogenase 1 Homo sapiens
4 The data suggest that TGZ-induced apoptosis in MDA-MB-231 cells cultured in medium without estradiol or deprived of ERbeta is mediated by PRODH/POX and the process is facilitated by proline availability for PRODH/POX by TGZ-dependent inhibition of collagen biosynthesis. Proline proline dehydrogenase 1 Homo sapiens