Title : Sodium Butyrate Enhances Curcuminoids Permeability through the Blood-Brain Barrier, Restores Wnt/β-Catenin Pathway Antagonists Gene Expression and Reduces the Viability of Glioblastoma Cells.

Pub. Date : 2021 Oct 19

PMID : 34681943






1 Functional Relationships(s)
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1 These effects are mediated via ROS generation and changes in gene expression, including upregulation of Wnt/beta-catenin pathway antagonists, SFRP1, and RUNX3, and downregulation of UHRF1, the key epigenetic regulator. Reactive Oxygen Species secreted frizzled related protein 1 Homo sapiens