Title : Dual acting oximes designed for therapeutic decontamination of reactive organophosphates via catalytic inactivation and acetylcholinesterase reactivation.

Pub. Date : 2021 Sep 23

PMID : 34671741






2 Functional Relationships(s)
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Protein Name
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1 Dual acting oximes designed for therapeutic decontamination of reactive organophosphates via catalytic inactivation and acetylcholinesterase reactivation. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 This library was screened by enzyme assays performed with human and electric eel subtypes of OP-inactivated AChE, which led to identifying three oxime leads that displayed significant enhancements in reactivation activity comparable to 2-PAM. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens