Title : 2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors.

Pub. Date : 2021 Oct 14

PMID : 34671446






1 Functional Relationships(s)
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1 Different five-membered nitrogen-containing heteroaromatics in the position of the typical electrophilic group in prolyl oligopeptidase (PREP) inhibitors were investigated and compared to tetrazole. Nitrogen prolyl endopeptidase Homo sapiens