Pub. Date : 2021 Oct
PMID : 34663976
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the nucleus, the altered PHGDH activity restricts NAD+ level and compartmentally repressed NAD+-dependent PARP1 activity for poly(ADP-ribosyl)ation of c-Jun, thereby leading to impaired c-Jun transcriptional activity linked to cell growth inhibition. | poly(adp-ribosyl) | poly(ADP-ribose) polymerase 1 | Homo sapiens |