Pub. Date : 2021
PMID : 34659631
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Therefore, in this study, we aim to confirm whether ginsenoside Rg3 targeting hERG K(+) channel could be used to reverse the vandetanib-induced QT interval prolongation. | vandetanib | ETS transcription factor ERG | Homo sapiens |
| 2 | In stable transfected human hERG gene HEK293 cells, vandetanib caused concentrate-dependent inhibition in the step and tail currents of hERG. | vandetanib | ETS transcription factor ERG | Homo sapiens |
| 3 | In stable transfected human hERG gene HEK293 cells, vandetanib caused concentrate-dependent inhibition in the step and tail currents of hERG. | vandetanib | ETS transcription factor ERG | Homo sapiens |
| 4 | Furthermore, ginsenoside Rg3 alleviated vandetanib-induced hERG current inhibition and accelerated the process of the channel activation. | vandetanib | ETS transcription factor ERG | Homo sapiens |