Title : Lithium chloride inhibits the migration and invasion of osteosarcoma cells by blocking nuclear translocation of phospho-Erk.

Pub. Date : 2021 Dec 3

PMID : 34656851






3 Functional Relationships(s)
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Protein Name
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1 Lithium chloride inhibits the migration and invasion of osteosarcoma cells by blocking nuclear translocation of phospho-Erk. Lithium Chloride mitogen-activated protein kinase 1 Homo sapiens
2 Investigations of LiCl-induced signaling have focused mainly on extracellular signal regulated kinase 1/2 (ERK1/2) and glycogen synthase kinase 3 (GSK-3). Lithium Chloride mitogen-activated protein kinase 1 Homo sapiens
3 In osteosarcoma cells treated with LiCl or EGF, active beta-catenin and p-ERK protein levels were significantly increased compared to those in the control group. Lithium Chloride mitogen-activated protein kinase 1 Homo sapiens