Title : Advance in dietary polyphenols as dipeptidyl peptidase-IV inhibitors to alleviate type 2 diabetes mellitus: aspects from structure-activity relationship and characterization methods.

Pub. Date : 2021 Oct 15

PMID : 34652225






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Advance in dietary polyphenols as dipeptidyl peptidase-IV inhibitors to alleviate type 2 diabetes mellitus: aspects from structure-activity relationship and characterization methods. Polyphenols dipeptidyl peptidase 4 Homo sapiens
2 Dietary polyphenols have attracted attention as dipeptidyl peptidase-IV (DPP-IV) inhibitors and indirectly improve insulin secretion. Polyphenols dipeptidyl peptidase 4 Homo sapiens
3 Dietary polyphenols have attracted attention as dipeptidyl peptidase-IV (DPP-IV) inhibitors and indirectly improve insulin secretion. Polyphenols dipeptidyl peptidase 4 Homo sapiens
4 The DPP-IV inhibitory activities of dietary polyphenols depend on their structural diversity. Polyphenols dipeptidyl peptidase 4 Homo sapiens
5 Screening methods that can be used to rapidly and accurately identify potential polyphenol DPP-IV inhibitors are urgently needed. Polyphenols dipeptidyl peptidase 4 Homo sapiens
6 This review focuses on the relationship between the structures of dietary polyphenols and their DPP-IV inhibitory effects. Polyphenols dipeptidyl peptidase 4 Homo sapiens
7 Different characterization methods used for polyphenols as DPP-IV inhibitors have been summarized and compared. Polyphenols dipeptidyl peptidase 4 Homo sapiens
8 Various combinations of methods, such as in-vitro enzymatic inhibition, ex-vivo/in-vivo enzymatic inhibition, cell-based in situ, and in-silico virtual screening, are used to evaluate the DPP-IV inhibitory effects of dietary polyphenols. Polyphenols dipeptidyl peptidase 4 Homo sapiens