Title : Comparative imaging and biodistribution studies with an anti-CEA monoclonal antibody and its F(ab)2 and Fab fragments in mice with colon carcinoma xenografts.

Pub. Date : 1986

PMID : 3464424






1 Functional Relationships(s)
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1 Gamma scintigraphy of nude mice bearing CEA-producing human tumour xenografts and injected with 131I-labelled fragments showed earlier and superior imaging of tumours than did 131I-intact antibody, and this was most marked with the Fab fragment. Iodine-131 carcinoembryonic antigen gene family Mus musculus