Title : High alanine aminotransaminase associated with daptomycin use in a premature infant.

Pub. Date : 2021 Oct 11

PMID : 34643345






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1 We report on a premature infant who developed hepatotoxicity as an adverse drug reaction after the administration of daptomycin 6 mg per kg per dose every 12 h. The patient had an unexpectedly sharp rise of alanine aminotransaminase, prothrombin time and international normalised ratio on the second day following daptomycin administration. Daptomycin coagulation factor II, thrombin Homo sapiens
2 We report on a premature infant who developed hepatotoxicity as an adverse drug reaction after the administration of daptomycin 6 mg per kg per dose every 12 h. The patient had an unexpectedly sharp rise of alanine aminotransaminase, prothrombin time and international normalised ratio on the second day following daptomycin administration. Daptomycin coagulation factor II, thrombin Homo sapiens