Title : NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells.

Pub. Date : 2021 Nov

PMID : 34636169






1 Functional Relationships(s)
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1 Both NUDT15 variant genotype and NT5C2 and PRPS1 mutations were significantly associated with mercaptopurine sensitivity in 83 BCP-ALL and 23 T-ALL cell lines. Mercaptopurine 5'-nucleotidase, cytosolic II Homo sapiens