Pub. Date : 2021
PMID : 34630084
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In terms of mechanism, we found that 6-Gingerol decreased histone H3K27me3 levels, activated AKT pathway and inhibited the activation of ERK and NF-kappaB pathway at 3 days post-HIBI. | gingerol | thymoma viral proto-oncogene 1 | Mus musculus |
2 | Taken together, our data clearly indicate that 6-Gingerol plays a neuroprotective role against HIBI by epigenetic modification and regulation of AKT, ERK, and NF-kappaB pathways, inhibiting inflammatory responses and reducing cell death. | gingerol | thymoma viral proto-oncogene 1 | Mus musculus |