Title : 6-Gingerol Alleviates Neonatal Hypoxic-Ischemic Cerebral and White Matter Injury and Contributes to Functional Recovery.

Pub. Date : 2021

PMID : 34630084






2 Functional Relationships(s)
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1 In terms of mechanism, we found that 6-Gingerol decreased histone H3K27me3 levels, activated AKT pathway and inhibited the activation of ERK and NF-kappaB pathway at 3 days post-HIBI. gingerol thymoma viral proto-oncogene 1 Mus musculus
2 Taken together, our data clearly indicate that 6-Gingerol plays a neuroprotective role against HIBI by epigenetic modification and regulation of AKT, ERK, and NF-kappaB pathways, inhibiting inflammatory responses and reducing cell death. gingerol thymoma viral proto-oncogene 1 Mus musculus