Title : Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease.

Pub. Date : 2021

PMID : 34603012






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mapping of BCAA metabolism was performed using mass spectrometry and enriched (15N) and (13C) isotopes of leucine, isoleucine, and valine in acutely isolated slices of surgically resected cerebral cortical tissue from human brain and in hiPSC-derived brain cells carrying mutations in either amyloid precursor protein (APP) or presenilin-1 (PSEN-1). Leucine AT-rich interaction domain 4B Homo sapiens