Pub. Date : 2021 Oct 1
PMID : 34595742
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histamine-activated histamine H1 receptor (H1R) signaling regulates many gene expressions, mainly through the protein kinase C (PKC)/extracellular signal-regulated kinases (ERK) signaling. | Histamine | histamine receptor H1 | Homo sapiens |
| 2 | Histamine-activated histamine H1 receptor (H1R) signaling regulates many gene expressions, mainly through the protein kinase C (PKC)/extracellular signal-regulated kinases (ERK) signaling. | Histamine | histamine receptor H1 | Homo sapiens |
| 3 | H1R gene itself is also up-regulated by the activation of H1R signaling with histamine. | Histamine | histamine receptor H1 | Homo sapiens |
| 4 | H1R gene itself is also up-regulated by the activation of H1R signaling with histamine. | Histamine | histamine receptor H1 | Homo sapiens |
| 5 | Stimulation with histamine up-regulates H1R gene expression through the activation of H1R in HeLa cells. | Histamine | histamine receptor H1 | Homo sapiens |
| 6 | Stimulation with histamine up-regulates H1R gene expression through the activation of H1R in HeLa cells. | Histamine | histamine receptor H1 | Homo sapiens |
| 7 | H1R-activated H1R gene up-regulation in response to histamine was also observed in U373 astroglioma cells. | Histamine | histamine receptor H1 | Homo sapiens |
| 8 | H1R-activated H1R gene up-regulation in response to histamine was also observed in U373 astroglioma cells. | Histamine | histamine receptor H1 | Homo sapiens |
| 9 | In addition, the promoter region responsible for histamine-induced H1R gene transcription in U373 cells was different from that of HeLa cells. | Histamine | histamine receptor H1 | Homo sapiens |