Title : Inhibition of CYP27B1 and CYP24 Increases the Anti-proliferative Effects of 25-Hydroxyvitamin D3 in LNCaP Cells.

Pub. Date : 2021 Oct

PMID : 34593422






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The inhibitory effect of 25(OH)D3 on cell proliferation was potentiated after inhibition of CYP17B1 and CYP24 by genistein, preventing further metabolism of 25(OH)D3 to 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and 24,25-dihydroxyvitamin D3 (24,25(OH)2D3). 25(oh)2d3 cytochrome P450 family 24 subfamily A member 1 Homo sapiens