Title : Neferine Inhibits 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis by Suppression of Cell Proliferation and Induction of Apoptosis via Modulation of the PI3K/AKT/NF-κB Signaling Pathway.

Pub. Date : 2021

PMID : 34587404






1 Functional Relationships(s)
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1 Furthermore, western blotting findings displayed an augmented expression of PI3K, AKT, NF-kappaB, PCNA, cyclin D1, Ki-67, and Bcl-2, while reducing expression of p53, Bax, caspase-3, and caspase-9 in DMBA-induced cancer-bearing animals. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Wistar clone pR53P1 p53 pseudogene Rattus norvegicus