Title : Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells.

Pub. Date : 2021 Sep 15

PMID : 34576117






1 Functional Relationships(s)
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1 Further analysis using inhibitors of p38 MAPK, JNK, and NF-kappaB indicated that acute glucose shifts promoted IL-1beta secretion by activating the signaling pathway in a ROS-MAPK-NF-kappaB-NLRP3 inflammasome in THP-1 cells. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens