Title : Dual Blockade of Lactate/GPR81 and PD-1/PD-L1 Pathways Enhances the Anti-Tumor Effects of Metformin.

Pub. Date : 2021 Sep 17

PMID : 34572586






1 Functional Relationships(s)
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1 Here, we demonstrate the synergistic effects of the lactate/GPR81 blockade (3-hydroxy-butyrate, 3-OBA) and metformin on inhibiting cancer cells growth in vitro. Lactic Acid hydroxycarboxylic acid receptor 1 Homo sapiens