Title : Common Threads: Aphidicolin-Inducible and Folate-Sensitive Fragile Sites in the Human Genome.

Pub. Date : 2021

PMID : 34567068






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The folate-sensitive FSs include FRAXA that is associated with Fragile X syndrome (FXS), the most common heritable form of intellectual disability. Folic Acid fragile site, folic acid type, rare, fra(X)(q27.3) A (macroorchidism, mental retardation) Homo sapiens
2 Recent work suggests that both APH-inducible fragile sites and FRAXA undergo Mitotic DNA synthesis (MiDAS) when exposed to APH or folate stress, respectively. Folic Acid fragile site, folic acid type, rare, fra(X)(q27.3) A (macroorchidism, mental retardation) Homo sapiens