Title : Identification of a thrombin sequence with growth factor activity on macrophages.

Pub. Date : 1986 Feb

PMID : 3456576






1 Functional Relationships(s)
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1 In contrast to fibroblasts, the exposure of G0/G1-arrested J774 cells, a murine macrophage-like tumor cell line, with either active or esterolytically inactive diisopropyl phosphorofluoridate-conjugated alpha-thrombin (the enzymatically active form of thrombin, EC 3.4.21.5) results in a mitogenic response as measured by increased [3H]thymidine incorporation. Isoflurophate coagulation factor II Mus musculus