Title : Reduced menin expression leads to decreased ERĪ± expression and is correlated with the occurrence of human luminal B-like and ER-negative breast cancer subtypes.

Pub. Date : 2021 Dec

PMID : 34561764






1 Functional Relationships(s)
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1 Consistent with our clinical data, we demonstrated that GATA3 and FOXA1, co-factors in ESR1 regulation, interact physically with menin in MCF7 cells, and MEN1 knockdown led to altered protein expression of GATA3, the latter being a known marker of the luminal A subtype, in MCF7 cells. Phenobarbital GATA binding protein 3 Homo sapiens