Title : Crosstalk between ORMDL3, serine palmitoyltransferase, and 5-lipoxygenase in the sphingolipid and eicosanoid metabolic pathways.

Pub. Date : 2021

PMID : 34560079






1 Functional Relationships(s)
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1 Enzymatic reactions initiating production of these lipid mediators involve 5-lipoxygenase (5-LO)-mediated conversion of arachidonic acid to leukotrienes and serine palmitoyltransferase (SPT)-mediated de novo synthesis of sphingolipids. Arachidonic Acid arachidonate 5-lipoxygenase Homo sapiens