Title : Hypophosphatasia: Vitamin B6 status of affected children and adults.

Pub. Date : 2022 Jan

PMID : 34547524






1 Functional Relationships(s)
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1 B6-dependent seizures in infants with life-threatening HPP were later explained by their profound deficiency of TNSALP activity blocking PLP dephosphorylation to PL and diminishing gamma-hydroxybutyric acid synthesis in the brain. Pyridoxal alkaline phosphatase, biomineralization associated Homo sapiens