Pub. Date : 2022 Apr
PMID : 34538111
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent Advances: Reactive oxygen species (ROS), especially derived from the mitochondria, are one of the critical mediators of NLRP3 inflammasome activation. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Recent Advances: Reactive oxygen species (ROS), especially derived from the mitochondria, are one of the critical mediators of NLRP3 inflammasome activation. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Furthermore, NLRP3 inflammasome-driven inflammation recruits inflammatory cells, including macrophages and neutrophils, which in turn cause ROS production, suggesting a feedback loop between ROS and NLRP3 inflammasome. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 4 | Furthermore, NLRP3 inflammasome-driven inflammation recruits inflammatory cells, including macrophages and neutrophils, which in turn cause ROS production, suggesting a feedback loop between ROS and NLRP3 inflammasome. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 5 | Furthermore, NLRP3 inflammasome-driven inflammation recruits inflammatory cells, including macrophages and neutrophils, which in turn cause ROS production, suggesting a feedback loop between ROS and NLRP3 inflammasome. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 6 | Furthermore, NLRP3 inflammasome-driven inflammation recruits inflammatory cells, including macrophages and neutrophils, which in turn cause ROS production, suggesting a feedback loop between ROS and NLRP3 inflammasome. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 7 | CRITICAL ISSUES: The precise mechanism of how ROS affects NLRP3 inflammasome activation still need to be addressed. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 8 | This review will summarize the current knowledge on the molecular mechanisms underlying the activation of NLRP3 inflammasome with particular emphasis on the intricate balance of feedback loop between ROS and inflammasome activation. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |