Title : Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase.

Pub. Date : 2021 Oct

PMID : 34522196






2 Functional Relationships(s)
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1 A significant decrease in acetylcholine level in the brain is common in most patients with Alzheimer"s disease, therefore acetylcholinesterase (AChE) inhibitors such as donepezil and rivastigmine are widely used for patients with limited therapeutic results and major side effects. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 A significant decrease in acetylcholine level in the brain is common in most patients with Alzheimer"s disease, therefore acetylcholinesterase (AChE) inhibitors such as donepezil and rivastigmine are widely used for patients with limited therapeutic results and major side effects. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens