Title : Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways.

Pub. Date : 2021 Sep 14

PMID : 34521930






1 Functional Relationships(s)
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1 Shikonin can significantly reduce the expression of apoptosis-related proteins, paw swelling in rat arthritic tissues, and the levels of inflammatory factors in peripheral blood, such as TNF-alpha, IL-6, IL-8, IL-10, IL-17A, and IL-1beta while showing less toxicity to the liver and kidney. shikonin tumor necrosis factor Rattus norvegicus