Title : Elemene Nanoemulsion Inhibits Metastasis of Breast Cancer by ROS Scavenging.

Pub. Date : 2021

PMID : 34511904






1 Functional Relationships(s)
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1 Mechanistic studies demonstrated that the elemene nanoemulsion effectively scavenged the reactive oxygen species (ROS) in vitro and in vivo, which decreased the stabilization of hypoxia-inducible factor-1alpha (HIF-1alpha) and consequently reduced angiogenesis in the tumor microenvironment as well as decreased the level of NLRP3 inflammasomes and IL-1beta production. elemene NLR family, pyrin domain containing 3 Mus musculus