Title : Activation of the cytosolic calcium-independent phospholipase A2 β isoform contributes to TRPC6 externalization via release of arachidonic acid.

Pub. Date : 2021 Oct

PMID : 34509476






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We hypothesized that lysoPC activates the lipid-cleaving enzyme phospholipase A2 (PLA2), which releases arachidonic acid (AA) from the cellular membrane to open arachidonate-regulated calcium channels, allowing calcium influx that promotes externalization and activation of TRPC6 channels. Arachidonic Acid phospholipase A2 group IB Homo sapiens
2 We hypothesized that lysoPC activates the lipid-cleaving enzyme phospholipase A2 (PLA2), which releases arachidonic acid (AA) from the cellular membrane to open arachidonate-regulated calcium channels, allowing calcium influx that promotes externalization and activation of TRPC6 channels. Arachidonic Acid phospholipase A2 group IB Homo sapiens