Title : Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2.

Pub. Date : 2021 Dec

PMID : 34500039






2 Functional Relationships(s)
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1 Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-kappaB and Nrf2. catalpol nuclear factor, erythroid derived 2, like 2 Mus musculus
2 From the overall results, this study displayed that catalpol exerted a beneficial effect on CORT-induced depressive-like behavior in mice possibly via the inhibition of hypothalamic-pituitary-adrenal axis hyperactivity, central inflammation and oxidative damage partially through dual regulation of NF-kappaB and Nrf2. catalpol nuclear factor, erythroid derived 2, like 2 Mus musculus