Pub. Date : 2022 Jan
PMID : 34496661
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro, the half-maximum inhibitory concentration (IC50) of the potent P-gp inhibitor tariquidar in P-gp-overexpressing cells was significantly different using either (11C)verapamil (44 nM), (11C)N-desmethyl-loperamide (19 nM) or (11C)metoclopramide (4 nM) as substrate probes. | tariquidar | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 2 | In vitro, the half-maximum inhibitory concentration (IC50) of the potent P-gp inhibitor tariquidar in P-gp-overexpressing cells was significantly different using either (11C)verapamil (44 nM), (11C)N-desmethyl-loperamide (19 nM) or (11C)metoclopramide (4 nM) as substrate probes. | tariquidar | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |