Title : Fampridine and Acetazolamide in EA2 and Related Familial EA: A Prospective Randomized Placebo-Controlled Trial.

Pub. Date : 2021 Aug

PMID : 34484942






4 Functional Relationships(s)
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1 Fampridine and Acetazolamide in EA2 and Related Familial EA: A Prospective Randomized Placebo-Controlled Trial. Acetazolamide calcium voltage-gated channel subunit alpha1 A Homo sapiens
2 Objective: To determine the efficacy and safety of the treatment with prolonged-release 4-aminopyridine (fampridine) and acetazolamide for patients with episodic ataxia type 2 (EA2), patients with EA2 were treated with a random sequence of fampridine, acetazolamide, and placebo in a 3-period crossover trial. Acetazolamide calcium voltage-gated channel subunit alpha1 A Homo sapiens
3 Objective: To determine the efficacy and safety of the treatment with prolonged-release 4-aminopyridine (fampridine) and acetazolamide for patients with episodic ataxia type 2 (EA2), patients with EA2 were treated with a random sequence of fampridine, acetazolamide, and placebo in a 3-period crossover trial. Acetazolamide calcium voltage-gated channel subunit alpha1 A Homo sapiens
4 Conclusion: Both fampridine and acetazolamide significantly reduce the number of attacks in patients with EA2 and related EA in comparison to placebo. Acetazolamide calcium voltage-gated channel subunit alpha1 A Homo sapiens