Title : Blockade of KAT II Facilitates LTP in Kynurenine 3-Monooxygenase Depleted Mice.

Pub. Date : 2021

PMID : 34483669






1 Functional Relationships(s)
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1 However, administration of PF-04859989, a kynurenine aminotransferase (KAT) II inhibitor, limiting the production of KYNA, facilitated fEPSP and enhanced LTP to a greater extent in hippocampal slices from KMO-/- mice compared to WT mice. Kynurenic Acid kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) Mus musculus