Title : c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency.

Pub. Date : 2021 Dec

PMID : 34476741






2 Functional Relationships(s)
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1 A high rate of aerobic glycolysis is induced by c-MYC, increasing the amounts of intracellular Glucose-6-phosphate (G6P), fructose-6-phosphate (F6P), and glyceraldehyde-3-phosphate (GA3P), which can all enter pentose phosphate pathway (PPP) to produce Ribose-5-Phosphate (R5P) and NADPH, which are necessary for the biosynthesis of biomolecules such as proteins, nucleic acids, or lipids. fructose-6-phosphate 2,4-dienoyl-CoA reductase 1 Homo sapiens
2 A high rate of aerobic glycolysis is induced by c-MYC, increasing the amounts of intracellular Glucose-6-phosphate (G6P), fructose-6-phosphate (F6P), and glyceraldehyde-3-phosphate (GA3P), which can all enter pentose phosphate pathway (PPP) to produce Ribose-5-Phosphate (R5P) and NADPH, which are necessary for the biosynthesis of biomolecules such as proteins, nucleic acids, or lipids. fructose-6-phosphate 2,4-dienoyl-CoA reductase 1 Homo sapiens