Title : Apoptosis Inducing Activity of Rhinacanthin-C in Doxorubicin-Resistant Breast Cancer MCF-7 Cells.

Pub. Date : 2021

PMID : 34471052






1 Functional Relationships(s)
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1 Furthermore, Western blotting analyses showed that treatment with rhinacanthin-C (3-28 microM) for 24 h significantly decreased the expression levels of the phosphorylated forms of MAPK proteins (i.e., extracellular signal regulated protein kinase 1/2 (ERK1/2), c-Jun N-terminal kinases (JNK) and p38), Akt, GSK-3beta and Nrf2 proteins in MCF-7/DOX cells. Doxorubicin mitogen-activated protein kinase 3 Homo sapiens