Title : Magnesium isoglycyrrhizinate prevents cadmium-induced activation of JNK and apoptotic hepatocyte death by reversing ROS-inactivated PP2A.

Pub. Date : 2021 Dec 7

PMID : 34468764






2 Functional Relationships(s)
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1 Magnesium isoglycyrrhizinate prevents cadmium-induced activation of JNK and apoptotic hepatocyte death by reversing ROS-inactivated PP2A. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 Eliminating ROS by N-acetyl-l-cysteine abrogated Cd-induced PP2A-JNK pathway disruption and concurrently reinforced MgIG-conferred protective effects, which could be further slightly strengthened by PP2A overexpression. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens