Pub. Date : 2021
PMID : 34456573
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells. | tetrandrine | interleukin 6 | Homo sapiens |
| 2 | Tetrandrine inhibited IL-6-induced cell migration and invasion, respectively. | tetrandrine | interleukin 6 | Homo sapiens |
| 3 | Tetrandrine regulates the expression of migration-related genes in IL-6-stimulated HCT116 cells. | tetrandrine | interleukin 6 | Homo sapiens |
| 4 | Tetrandrine significantly downregulated the expression and enzyme activity of MMP-2 in IL-6-stimulated HCT116 cells. | tetrandrine | interleukin 6 | Homo sapiens |
| 5 | Conclusion: The findings of the present study suggested that tetrandrine may inhibit EMT in IL-6-stimulated HCT116 cells; therefore, it may represent a potential drug for CRC. | tetrandrine | interleukin 6 | Homo sapiens |