Title : MicroRNA-155 Modulates Macrophages' Response to Non-Tuberculous Mycobacteria through COX-2/PGE2 Signaling.

Pub. Date : 2021 Jul 21

PMID : 34451384






7 Functional Relationships(s)
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1 MicroRNA-155 Modulates Macrophages" Response to Non-Tuberculous Mycobacteria through COX-2/PGE2 Signaling. Dinoprostone microRNA 155 Homo sapiens
2 Antagomir against miR-155 effectively suppressed expression of COX-2 and reduced Prostaglandin E2(PGE2) secretion, suggesting that COX-2/PGE2 expression is dependent on miR-155. Dinoprostone microRNA 155 Homo sapiens
3 Antagomir against miR-155 effectively suppressed expression of COX-2 and reduced Prostaglandin E2(PGE2) secretion, suggesting that COX-2/PGE2 expression is dependent on miR-155. Dinoprostone microRNA 155 Homo sapiens
4 Antagomir against miR-155 effectively suppressed expression of COX-2 and reduced Prostaglandin E2(PGE2) secretion, suggesting that COX-2/PGE2 expression is dependent on miR-155. Dinoprostone microRNA 155 Homo sapiens
5 Antagomir against miR-155 effectively suppressed expression of COX-2 and reduced Prostaglandin E2(PGE2) secretion, suggesting that COX-2/PGE2 expression is dependent on miR-155. Dinoprostone microRNA 155 Homo sapiens
6 Antagomir against miR-155 effectively suppressed expression of COX-2 and reduced Prostaglandin E2(PGE2) secretion, suggesting that COX-2/PGE2 expression is dependent on miR-155. Dinoprostone microRNA 155 Homo sapiens
7 These findings provide novel mechanistic insights into the role of miR-155/COX-2/PGE2 signalling and suggest that induction of these pathways enhances survival of mycobacteria in macrophages. Dinoprostone microRNA 155 Homo sapiens