Title : Increased H2O2 levels and p53 stabilization lead to mitochondrial dysfunction in XPC-deficient cells.

Pub. Date : 2021 Nov 12

PMID : 34447990






1 Functional Relationships(s)
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1 Thus, the results suggest a critical role for mitochondrially-generated H2O2 in the regulation of p53 expression, which in turn modulates XP-C sensitivity to agents that cause mitochondrial stress. Hydrogen Peroxide tumor protein p53 Homo sapiens